Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
| Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
| Upregulated in class | absentNotch |
| GeneSet | NCI_HEDGEHOG SIGNALING EVENTS MEDIATED BY GLI PROTEINS |
| Enrichment Score (ES) | 0.6528833 |
| Normalized Enrichment Score (NES) | 1.6349883 |
| Nominal p-value | 0.002232143 |
| FDR q-value | 0.2548543 |
| FWER p-Value | 0.758 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HDAC2 | 4050433 | 20 | 5.359 | 0.1033 | Yes | ||
| 2 | SPOP | 450035 | 60 | 4.589 | 0.1905 | Yes | ||
| 3 | SIN3A | 2190121 | 85 | 4.292 | 0.2728 | Yes | ||
| 4 | PIAS1 | 5340301 | 284 | 3.281 | 0.3260 | Yes | ||
| 5 | GSK3B | 5360348 | 510 | 2.696 | 0.3664 | Yes | ||
| 6 | CREBBP | 5690035 7040050 | 535 | 2.625 | 0.4162 | Yes | ||
| 7 | CSNK1E | 2850347 5050093 6110301 | 704 | 2.315 | 0.4522 | Yes | ||
| 8 | GNB1 | 2120397 | 750 | 2.237 | 0.4933 | Yes | ||
| 9 | PRKCD | 770592 | 966 | 1.931 | 0.5194 | Yes | ||
| 10 | HDAC1 | 2850670 | 1077 | 1.803 | 0.5485 | Yes | ||
| 11 | CSNK1G3 | 110450 | 1322 | 1.527 | 0.5651 | Yes | ||
| 12 | LGALS3 | 2120239 | 1355 | 1.492 | 0.5925 | Yes | ||
| 13 | KIF3A | 5050348 6650079 | 1505 | 1.335 | 0.6104 | Yes | ||
| 14 | RBBP7 | 430113 450450 2370309 | 1507 | 1.334 | 0.6363 | Yes | ||
| 15 | SAP30 | 5080735 | 1638 | 1.209 | 0.6529 | Yes | ||
| 16 | IFT172 | 3800372 7100400 | 2020 | 0.955 | 0.6510 | No | ||
| 17 | MAP2K1 | 840739 | 2487 | 0.683 | 0.6392 | No | ||
| 18 | GNG2 | 2230390 | 2501 | 0.675 | 0.6516 | No | ||
| 19 | CSNK1G2 | 3060095 4730037 | 3011 | 0.459 | 0.6332 | No | ||
| 20 | GNAO1 | 2510292 6590487 | 4349 | 0.129 | 0.5637 | No | ||
| 21 | RAB23 | 2970075 | 4370 | 0.127 | 0.5651 | No | ||
| 22 | CSNK1A1 | 2340427 | 4478 | 0.115 | 0.5616 | No | ||
| 23 | FOXA2 | 540338 5860441 | 4553 | 0.108 | 0.5597 | No | ||
| 24 | SAP18 | 3610092 | 4779 | 0.091 | 0.5493 | No | ||
| 25 | SHH | 5570400 | 5066 | 0.073 | 0.5354 | No | ||
| 26 | GNAI1 | 4560390 | 5227 | 0.065 | 0.5280 | No | ||
| 27 | GLI1 | 4560176 | 7166 | 0.014 | 0.4240 | No | ||
| 28 | AKT1 | 5290746 | 7382 | 0.010 | 0.4126 | No | ||
| 29 | XPO1 | 540707 | 7492 | 0.008 | 0.4068 | No | ||
| 30 | GNAI3 | 4670739 | 8803 | -0.014 | 0.3366 | No | ||
| 31 | FBXW11 | 6450632 | 8838 | -0.015 | 0.3351 | No | ||
| 32 | MTSS1 | 780435 2370114 | 9197 | -0.021 | 0.3162 | No | ||
| 33 | GLI2 | 3060632 | 12432 | -0.114 | 0.1443 | No | ||
| 34 | GLI3 | 5690148 | 13619 | -0.207 | 0.0845 | No | ||
| 35 | PTCH1 | 430278 | 13776 | -0.226 | 0.0805 | No | ||
| 36 | SMO | 5340538 6350132 | 14238 | -0.287 | 0.0612 | No | ||
| 37 | GNAZ | 6130296 | 14277 | -0.293 | 0.0649 | No | ||
| 38 | CSNK1G1 | 840082 1230575 3940647 | 15113 | -0.469 | 0.0291 | No | ||
| 39 | PRKACA | 2640731 4050048 | 15482 | -0.598 | 0.0209 | No | ||
| 40 | RBBP4 | 6650528 | 15845 | -0.764 | 0.0163 | No | ||
| 41 | CSNK1D | 4280280 4480167 6450600 | 16041 | -0.866 | 0.0226 | No | ||
| 42 | SIN3B | 6650253 | 16174 | -0.944 | 0.0339 | No | ||
| 43 | ARRB2 | 2060441 | 17894 | -2.368 | -0.0125 | No | ||
| 44 | SUFU | 6650181 | 18066 | -2.638 | 0.0296 | No |
